Source: https://tendernation.io/opportunities/01a13dfa-7b30-73d2-92b2-8130cec59016/genome-plasmid

awarded GB open procedure

# Genome Plasmid

[University Of Edinburgh](https://tendernation.io/buyers/university-of-edinburgh)

Estimated value

Not stated

Published

31 Mar 2026

Deadline

Rolling deadline

## Who can bid

- Open procedure

    Anyone can submit a full tender; there is no shortlisting stage.

## About this tender

We are planning a clinical trial to treat a rare genetic disease that causes progressive dementia in children. Our therapy is based on the following: Autologous haematopoietic stem progenitor cells (HSPCs) are modified ex vivo with a lentiviral vector (LV) to express supraphysiologic levels of a secreted enzyme in myeloid progeny, in essence using gene-modified monocytes/macrophages as a durable and effective vehicle for central nervous system (CNS) enzyme delivery.

In order to progress this therapy, we require the following; a plasmid to our specification, produced to FDA, IND ready standard for use in the manufacture of a lentiviral vector for clinical trial. This Plasmid will be delivered directly from the supplier to the University of Edinburgh’s partner in the project, University of California Los Angeles.

## CPV classification

Medical consumables

Source

Public Contracts Scotland · Notice rls-4-MAR552953

[View official notice](https://www.publiccontractsscotland.gov.uk/search/show/search_view.aspx?ID=MAR552953)

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