Source: https://tendernation.io/opportunities/01a13cd2-2c8c-70cf-bca0-bbc3d47235f5/dianthus-nano-system awarded GB negotiated without publication procedure Suitable for SMEs # Dianthus Nano System [Durham University](https://tendernation.io/buyers/durham-university) Estimated value £300,047 Published 4 Jan 2023 Deadline Closed 3 Jan 2023 ## Who can bid - Buyer says suitable for SMEs The buyer ticked “suitable for SMEs” on the notice. Anyone can still bid. - Buyer says suitable for VCSEs The buyer ticked “suitable for voluntary, community and social enterprises” on the notice. [More contracts for small businesses and VCSEs](https://tendernation.io/opportunities/for-small-businesses) ## About this tender ### VEAT NOTICE The University has a requirement to purchase an instrument that features the latest innovation for characterising biomolecular binding affinities. The University has published this VEAT notice and intends to award a contract to NanoTemper Technologies GmbH following the expiry of 10 days from the date of publication of this notice. Additional information: The works, supplies or services can be provided only by a particular economic operator for the following reason: absence of competition for technical reasons ### Explanation: Specific features of the system include the • Measurements are performed in solution (i.e. no immobilisation is required) • Capability to quantify interactions in complex solutions (crude extract, serum) • Means to determine binding constant over a wide range (5 nM - high millimolar) as well as stoichiometry and thermodynamic parameters • Power to work at low nanomolar concentrations • Advantage of small sample volumes (20 microliter) coupled with the capacity to run samples in high-throughput mode using standard 384 well-plate • Used detection modalities based on two techniques: Spectral shift detection and Temperature-Related Intensity Change (TRIC) • Microfluidics-free • Mass independent measurement i.e., the measurable molecular weight range is from 101-107 Da • Measure up to 384 datapoints per run • Advantage of small sample volumes (20 microliter) coupled with the capacity to run samples in high-throughput mode using standard SBS 384 well-plate format Read full description ## CPV classification Machines and apparatus for testing and measuring Source Contracts Finder (UK) [View official notice](https://www.contractsfinder.service.gov.uk/notice/f9f1f317-81a5-4a57-b120-7f6c5cb5e22b) Never miss a tender like this again Get AI summaries, deadline alerts and a bid pipeline for tenders matched to your business. 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