Source: https://tendernation.io/opportunities/01a13c92-7110-73b3-85da-7f56924f63ff/advert-for-collaborator-in-biological-research-for-topical-product-to-assist-wit closed GB open procedure Suitable for SMEs # Advert for Collaborator in Biological Research for Topical Product to assist with Scalp Cooling during Chemotherapy [Paxman Coolers Limited](https://tendernation.io/buyers/paxman-coolers-limited) Estimated value £87,500 to £100,000 Published 13 Jul 2022 Deadline Closed 25 Jul 2022 ## Who can bid - Buyer says suitable for SMEs The buyer ticked “suitable for SMEs” on the notice. Anyone can still bid. - Buyer says suitable for VCSEs The buyer ticked “suitable for voluntary, community and social enterprises” on the notice. - Small contract value Valued under £135,018 including VAT, the lowest Procurement Act threshold for goods and services. - Open procedure Anyone can submit a full tender; there is no shortlisting stage. [More contracts for small businesses and VCSEs](https://tendernation.io/opportunities/for-small-businesses) ## About this tender Paxman is a medical technology company with an established leadership position in the Scalp Cooling sector. The Paxman Scalp Cooling System (PSCS) minimizes hair loss in connection with chemotherapy treatment. The product is distributed to over 60 markets internationally, including: France, Germany, The Netherlands, Switzerland, Sweden, Russia, Brazil, Mexico, Australia, and the U.S. Scalp cooling is an important treatment, which has a strong clinical support and is a fully established therapy in many countries throughout the world. Chemotherapy-induced alopecia is the most feared side effect of treatment in >75% of patients. Often patients feel this is the most traumatic side effect of their cancer treatment and not only can it lead to social isolation, but hair loss can affect self-image more than breast surgery. Eight percent of patients refuse chemotherapy or request a less efficacious treatment due to the prospect of hair loss. The company has extensive global experience - since 2003, more than 65 clinical studies have been conducted in more than 17 countries and includes the first-ever randomized clinical trial to evaluate modern scalp cooling, which took place at several Cancer Centers in the United States as part of the FDA (Food and Drug Administration) clearance process. As part of Paxman's investment in biological research, it has been discovered that chemotherapy drugs induce oxidative stress inside cells of the hair follicles which causes cell toxicity (and ultimately hair loss). Therefore, a novel patented combinatorial approach was designed to reduce cell toxicity at "sub-optimal" cooling temperatures and has the potential to dramatically enhance the efficacy of the Paxman scalp cooling device. This intervention combines cooling with treatment with a reactive oxygen species (ROS) inhibitor (antioxidant compound) delivered into cells to reduce oxidative stress (and these findings have been confirmed using whole follicles mini-organ cultures). Using in vitro models, the company have now established a panel of antioxidant compounds which has shown extremely good efficacy in minimising or preventing cytotoxicity in combination with cooling. Paxman now need the expertise to be able to target these antioxidant compounds to human hair follicles of the scalp. This will require expertise in pharmaceutics in order to prepare topical agents with appropriate formulations for delivery of these antioxidants to the hair follicles. The identified third-party organisation must have both the cell biology/skin research as well as pharmaceutics expertise and research capabilities in order to be in position to deliver the proposed project. Read full description ## CPV classification Medical equipments, pharmaceuticals and personal care products Source Contracts Finder (UK) [View official notice](https://www.contractsfinder.service.gov.uk/notice/58505d9c-3c1d-450e-9e47-ab8f17a6f425) Never miss a tender like this again Get AI summaries, deadline alerts and a bid pipeline for tenders matched to your business. Free to start. [Track tenders free](https://tendernation.io/register) [Buyer profile Paxman Coolers Limited: past awards and live tenders](https://tendernation.io/buyers/paxman-coolers-limited) [Sector More Medical equipment & pharmaceuticals tenders](https://tendernation.io/sectors/medical-equipment-pharmaceuticals) ## More tenders like this [Autoclaves – Autoklaver till Tandvårdshögskolan i Malmö · Malmö universitet · 9 days left · 28 Oct 2026](https://tendernation.io/opportunities/01a156a9-9dd7-7329-993d-a6e0f71667e9/sweden-autoclaves-autoklaver-till-tandvardshogskolan-i-malmo) [Pharmaceutical products – Open-House-Rabattverträge 2026-17 Tafamidis · Techniker Krankenkasse · 773 days left · 30 Nov 2028](https://tendernation.io/opportunities/01a156a9-aa23-7217-b0b6-daa9dc9fe3b2/germany-pharmaceutical-products-open-house-rabattvertrage-2026-17-tafamidis) [Enteral feeds – Enteralna prehrana · Klinički Bolnički Centar Split · 31 days left · 20 Nov 2026](https://tendernation.io/opportunities/01a156a9-61f0-727d-a7e5-8af11fde40a5/croatia-enteral-feeds-enteralna-prehrana) [Operating-theatre devices – Operační stoly · Fakultní nemocnice Brno · 31 days left · 19 Nov 2026](https://tendernation.io/opportunities/01a156a9-6f95-7385-a1b5-a45251fdf818/czechia-operating-theatre-devices-operacni-stoly) [Orthopaedic implants – Dostawa implantów ortopedycznych · Uniwersytecki Szpital Kliniczny w Białymstoku · 31 days left · 19 Nov 2026](https://tendernation.io/opportunities/01a156a9-a014-7092-93fd-a23b17232c85/poland-orthopaedic-implants-dostawa-implantow-ortopedycznych) [Laboratory reagents – Dostawa odczynników oraz dzierżawa analizatorów. · Szpital Specjalistyczny w Chorzowie · 7 days left · 27 Oct 2026](https://tendernation.io/opportunities/01a156a9-ca42-73b8-a366-fed6ba8a391f/poland-laboratory-reagents-dostawa-odczynnikow-oraz-dzierzawa-analizatorow)