Source: https://tendernation.io/opportunities/01a13c83-b523-7213-9404-1439282bee93/microcirculatory-changes-during-haemorrhagic-shock-in-relation-to-shock-and-subs

awarded GB restricted procedure

# Microcirculatory changes during haemorrhagic shock in relation to shock and subsequent inflammatory responses

[Defence Science and Technology Laboratory](https://tendernation.io/buyers/defence-science-and-technology-laboratory)

Estimated value

£54,992

Published

27 Oct 2021

Deadline

Closed

17 Sept 2021

## Who can bid

- Small contract value

    Valued under £135,018 including VAT, the lowest Procurement Act threshold for goods and services.

## About this tender

The cardiovascular response to trauma (tissue injury, haemorrhagic shock and resuscitation) leads to inflammatory responses that can either cause further damage or underpin subsequent tissue healing. A novel element of the inflammatory response is the interaction between platelets and neutrophils, which have been examined in a collaborative pilot study with King's College, who have expertise in neutrophil-platelet interactions. The inflammatory response in trauma is in part orchestrated by the microcirculation. There is considerable inter-individual variation in the microcirculatory response to trauma. A detailed assessment of these responses, followed by correlation with the systemic physiological and inflammatory responses, may identify mechanisms of response and potential therapeutic directions to modify the inflammatory response and augment the potential for healing.

## CPV classification

Research laboratory services

Source

Contracts Finder (UK)

[View official notice](https://www.contractsfinder.service.gov.uk/notice/f00d81b7-9ef7-4f8a-b794-f7bfb4e3b52d)

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