Source: https://tendernation.io/opportunities/01a13c4e-f38b-7189-8b08-ef12074654da/automated-solution-to-develop-and-optimise-upstream-processe awarded GB negotiated without publication procedure Suitable for SMEs # Automated Solution to Develop and Optimise Upstream Processe [Vaccines Manufacturing and Innovation Centre (UK) Limited](https://tendernation.io/buyers/vaccines-manufacturing-and-innovation-centre-uk-limited) Estimated value £793,233 Published 17 Nov 2020 Deadline Closed 12 Nov 2020 ## Who can bid - Buyer says suitable for SMEs The buyer ticked “suitable for SMEs” on the notice. Anyone can still bid. - Buyer says suitable for VCSEs The buyer ticked “suitable for voluntary, community and social enterprises” on the notice. [More contracts for small businesses and VCSEs](https://tendernation.io/opportunities/for-small-businesses) ## About this tender VMIC requires the ability to rapidly develop and optimise upstream processes using a state-of-the-art Quality by Design (QBD) approach to ensure robustness as well as rapid development. The ability to execute a Design of Experiments (DoE) approach is integral to the assurance of robustness and furthermore ensures that the processes developed are well away from the edge of failure. VMIC will be a centre of excellence for vaccine development in the UK, and must also have the capability to respond rapidly to pandemic situations, therefore it requires a solution that will allow rapid development of robust processes for clients whilst also allowing a significant reduction in operator-hours and time to create credible processes for anti-pandemic vaccine candidates. The Sartorius Ambr250 HT system, including installation and 1 year comprehensive service, allows the simultaneous operation of multiple bioreactor vessels working under different operating parameters, with each parameter, addition, feed etc. controlled by robotics in response to a pre-defined operational plan. The time saved using such an automated system is significant and allows for the rapid development of processes in a fraction of the time required using a more traditional approach. It also allows for the scale-down validation of existing processing parameters, thus speeding up the robustness testing and subsequent validation of existing process parameters. The Ambr 250 HT system is unique in the market place due to the high level of automation and robotics employed to rapidly reduce the time spent in development of mammalian or microbial process, and the high level of automation, microbiological containment, robotics and integrated liquid handling, sampling, and on board sample storage. VMIC will be a centre of excellence for vaccine development in the UK, and must have the capability to respond rapidly to pandemic situations. The Ambr system will be integral to both these missions because the solution will allow rapid development of robust processes for clients whilst also allowing a significant reduction in operator-hours and time to create credible processes for anti-pandemic vaccine candidates. Read full description ## CPV classification Pharmaceutical products Source Contracts Finder (UK) [View official notice](https://www.contractsfinder.service.gov.uk/notice/1c8b1bce-edc2-484b-bb2d-b637293b9a7a) Never miss a tender like this again Get AI summaries, deadline alerts and a bid pipeline for tenders matched to your business. Free to start. [Track tenders free](https://tendernation.io/register) [Buyer profile Vaccines Manufacturing and Innovation Centre (UK) Limited: past awards and live tenders](https://tendernation.io/buyers/vaccines-manufacturing-and-innovation-centre-uk-limited) [Sector More Medical equipment & pharmaceuticals tenders](https://tendernation.io/sectors/medical-equipment-pharmaceuticals) ## More tenders like this [Blood-grouping reagents – ΑΝΤΙΔΡΑΣΤΗΡΙΑ ΑΙΜΟΔΟΣΙΑΣ · ΓΕΝΙΚΟ ΝΟΣΟΚΟΜΕΙΟ ΔΡΑΜΑΣ · 46 days left · 4 Dec 2026](https://tendernation.io/opportunities/01a15183-2813-7182-8d99-b716cf03c730/greece-blood-grouping-reagents-antidrasthria-aimodosias) [Medical consumables – Kärlkateterlås · Region Jönköpings län · 30 days left · 17 Nov 2026](https://tendernation.io/opportunities/01a15183-2a9a-72d4-bb06-f03d9172406e/sweden-medical-consumables-karlkateterlas) [Miscellaneous medical devices and products – DOSTAWA AKCESORIÓW DO SPRZĘTÓW MEDYCZNYCH DLA UNIWERSYTECKIEGO SZPITALA KLINICZNEGO W RADOMSKU. · Uniwersytecki Szpital Kliniczny · 11 days left · 30 Oct 2026](https://tendernation.io/opportunities/01a15183-0b5a-71e9-a08d-e181d06851b0/poland-miscellaneous-medical-devices-and-products-dostawa-akcesoriow-do-sprz) [Medical consumables – Zakup środków ochrony indywidualnej, rękawiczek, pokrowców i sprzętu unieruchamiającego · Wojewódzka Stacja Pogotowia Ratunkowego i Transportu Sanitarnego "Meditrans" Samodzielny Publiczny Zakład Opieki Zdrowotnej w Warszawie · 29 days left · 17 Nov 2026](https://tendernation.io/opportunities/01a15183-1d96-73a3-a8b8-1b3d8556abf8/poland-medical-consumables-zakup-srodkow-ochrony-indywidualnej-rekawiczek) [Devices and instruments for infusion – Infusionspump TPN · Västra Götalandsregionen · 30 days left · 17 Nov 2026](https://tendernation.io/opportunities/01a15183-28be-7144-8e47-d1110f2f2cc8/sweden-devices-and-instruments-for-infusion-infusionspump-tpn) [Medical equipments – Dostawy asortymentu wielorazowego na okres 24 miesięcy - sprawa nr Z/95/PN/26 · Regionalny Szpital Specjalistyczny im. dr Władysława Biegańskiego · 11 days left · 30 Oct 2026](https://tendernation.io/opportunities/01a15183-3711-7240-9b25-1a923d673777/poland-medical-equipments-dostawy-asortymentu-wielorazowego-na-okres-24-mies)