Source: https://tendernation.io/opportunities/01a13c06-ccd6-730a-a632-da1d9be2c42c/inra-bcg-challenge awarded GB open procedure Suitable for SMEs # INRA BCG Challenge [Department for Environment, Food & Rural Affairs](https://tendernation.io/buyers/department-for-environment-food-rural-affairs) Estimated value £10,800 Published 18 Nov 2016 Deadline Closed 20 Jul 2015 ## Who can bid - Buyer says suitable for SMEs The buyer ticked “suitable for SMEs” on the notice. Anyone can still bid. - Buyer says suitable for VCSEs The buyer ticked “suitable for voluntary, community and social enterprises” on the notice. - Small contract value Valued under £135,018 including VAT, the lowest Procurement Act threshold for goods and services. - Open procedure Anyone can submit a full tender; there is no shortlisting stage. [More contracts for small businesses and VCSEs](https://tendernation.io/opportunities/for-small-businesses) ## About this tender This project builds and extends on significant progress made over the last decade in the development of TB vaccines for cattle and addresses key policy requirements that arise from the short duration of immunity induced in cattle by BCG. First, APHA will determine whether annual revaccination of cattle with BCG can maintain sufficient levels of protection over time. APHA will also test if re-vaccination with BCG results in re-sensitisation of vaccinated animals to the tuberculin skin test and whether the DIVA test can still be used in the face of a number of rounds of BCG vaccination and tuberculin skin testing. APHAwill also investigate whether novel vaccination regimes can be developed to improve and extend BCG-induced protection against M. bovis infection and whether the lead subunit vaccine candidates identified in SE3224 ‘Continuation of the development for vaccines against bovine TB in cattle’ can be used to boost and extend the duration of BCG-induced immunity without sensitising animals to the tuberculin skin test. APHAs second main objective is to develop vaccines that do not sensitise cattle to the tuberculin test. This would allow the continuation of existing tuberculin skin test-based test and slaughter strategies alongside vaccination and is the approach to vaccine development favoured by stakeholders and the EU. The expected outcomes of this project will be to optimise the way BCG vaccination should be applied in cattle, to improve its efficacy and to develop vaccines that, whilst effective, do not sensitise vaccinated animals to the tuberculin skin test. Additional information: Please note that Defra procurement uses e-tendering, provided by Bravosolutions. In order to access the Bravo system you will need to be registered. Could I therefore request that you register on the Bravo portal for Defra. If you’re already registered on the Bravo portal please check that your registration includes Defra, as you have to specify us in order to correctly receive the tender documents. If you have any problems with the registration process, please contact the Bravo helpline on 0800 368 4850 or alternatively email them at . The link you require for new registration/amendments to registrations is - [defra.bravosolution.co.uk](https://defra.bravosolution.co.uk) Read full description ## CPV classification Research and experimental development services Source Contracts Finder (UK) [View official notice](https://www.contractsfinder.service.gov.uk/notice/f43b510b-adc8-11e6-9901-0019b9f3037b) Never miss a tender like this again Get AI summaries, deadline alerts and a bid pipeline for tenders matched to your business. Free to start. 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