Source: https://tendernation.io/opportunities/01a13be0-7c58-738d-a99d-0474af400bba/onasemnogene-abeparvovec-intravenous-zolgensma-service-onasemnogene-abeparv

awarded GB open procedure

# Onasemnogene Abeparvovec Intravenous (Zolgensma®) Service & Onasemnogene Abeparvovec Intrathecal (OAV101 IT) Service

[NHS England](https://tendernation.io/buyers/nhs-england)

Estimated value

£26,136,000

Published

22 Sept 2026

Deadline

Closed

8 Jul 2026

## Who can bid

- Split into 5 lots

    You can usually bid for just the lots you can deliver.
- Open procedure

    Anyone can submit a full tender; there is no shortlisting stage.

## About this tender

Intention to award the Onasemnogene Abeparvovec Intravenous (Zolgensma®) Service & Onasemnogene Abeparvovec Intrathecal (OAV101 IT) Service. This is a a one-time, in vivo gene replacement therapy, for use in babies aged 12 months and under, that utilises an adeno-associated virus serotype 9 (AAV9) vector, modified to contain a functional copy of the human SMN1 gene. It is administered intravenously, allowing the vector to deliver the gene into motor neurones and peripheral tissues, enabling the sustained expression of survival motor neuron (SMN) protein, which is deficient or mutated in individuals with SMA.Onasemnogene abeparvovec intrathecal (OAV101 IT) is a one-time in vivo gene replacement therapy for patients with SMA, proposed to treat individuals with SMA aged 2 years and over. This intrathecal injection will be used to treat a distinct cohort of SMA patients to Zolgensma. It will be assessed via NICE’s technology appraisal programme, with an expected final guidance publication date in late 2026.Procurement was carried out in Lots for the services as detailed above. Contract values are estimated and will be dependent on number of patients actually treated at each awarded provider.

## CPV classification

Health services

Source

Find a Tender (UK) · Notice ocds-h6vhtk-06ae08-2026-09-22T16:39:34+01:00

[View official notice](https://www.find-tender.service.gov.uk/Notice/ocds-h6vhtk-06ae08-2026-09-22T16:39:34+01:00)

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