Source: https://tendernation.io/opportunities/01a13bbd-6aec-70cf-a05b-bbdf1e6e573d/formulation-machine awardedGBdirect award procedure # Formulation machine [The Pirbright Institute](https://tendernation.io/buyers/the-pirbright-institute) Estimated value Not stated Published 17 Jun 2025 Deadline Rolling deadline ## About this tender As a first step towards evaluating the use of RNA vaccines for livestock, the Centre for Veterinary Vaccine Innovation and Manufacturing (CVIM) collaborated ) to carry out a proof-of-principle study. The success of this work has led to the continued evaluation by CVIM of RNA-based vaccines for livestock. To facilitate the continued evaluation of RNA-based vaccines for livestock CVIM needs to develop the capacity to produce formulated mRNA vaccine candidates at a suitable scale to carry out in vivo immunogenicity studies. A machine to encapsidate RNA is required to produce formulated mRNA vaccines. A suitable formulation machine needs to: - Be compact (small footprint) to enable its location in existing CVIM R&D facilities. - Enable application of Good Laboratory Practice - Have seamless scalability to enable higher levels of production at good manufacturing practice (GMP, to meet regulatory compliance). - Be capable of encapsidating mRNA of differing complexity using different LNP formulations. - Be user-friendly (reduced training requirements and user error). - Provide a protective environment for products (low bioburden). - Produce suitable volumes (capacity to support in vivo studies). - Compatible with existing and collaborator's equipment to enable the transfer of reagents and methods. Specifically, the encapsidation machine needs to be compatible to our recently purchased Ntensify Mini (RNA producing machine). Read full description Source Find a Tender (UK) · Notice ocds-h6vhtk-054e66-2025-06-17T14:35:58+01:00 [View official notice ](https://www.find-tender.service.gov.uk/Notice/ocds-h6vhtk-054e66-2025-06-17T14:35:58+01:00) Never miss a tender like this again Get AI summaries, deadline alerts and a bid pipeline for tenders matched to your business. Free to start. [Track tenders free ](/register) [Buyer profileThe Pirbright Institute: past awards and live tenders](https://tendernation.io/buyers/the-pirbright-institute) ## More tenders like this [Gwelliannau i / Improvement works to the ‘Materials Recovery Facility’ (MRF) Ystâd Ddiwydiannol Cibyn, Caernarfon, Gwynedd, LL55 2BD Cyngor Gwynedd 55 days left 10 Dec 2026](https://tendernation.io/opportunities/01a145df-0f49-7002-8294-fee17b4b2429/gwelliannau-i-improvement-works-to-the-materials-recovery-facility-mrf-yst)[Mechanical and Electrical Consultant Tender University Hospitals of North Midlands NHS Trust 38 days left 23 Nov 2026](https://tendernation.io/opportunities/01a145df-0fba-7085-98fc-1c9389531130/mechanical-and-electrical-consultant-tender)[Employee Screening Dorset & Wiltshire Fire and Rescue Authority 17 days left 2 Nov 2026](https://tendernation.io/opportunities/01a145df-100b-70ec-8bcc-3630f263230d/employee-screening)[Legionella Consultancy Services South Norfolk Council 31 days left 16 Nov 2026](https://tendernation.io/opportunities/01a145df-10ba-7014-b1c1-016db3ffb9a8/legionella-consultancy-services)[Post Office Branch - Eastfield Side Post Office Limited 12 days left 27 Oct 2026](https://tendernation.io/opportunities/01a145df-113b-707b-bbfc-9beab9c89fbd/post-office-branch-eastfield-side)[Heaton Reception Road Enhancement Northern Trains Limited 35 days left 20 Nov 2026](https://tendernation.io/opportunities/01a145df-117d-72ed-82eb-fa982f8ae9fe/heaton-reception-road-enhancement)